Changes of serum cytokine profiles in Korean vivax malarial patients after chemotherapy
Identifieur interne : 001D64 ( Main/Exploration ); précédent : 001D63; suivant : 001D65Changes of serum cytokine profiles in Korean vivax malarial patients after chemotherapy
Auteurs : T. S. Kim [Corée du Sud] ; Y. B. Chung [Corée du Sud] ; H. J. Choi [Corée du Sud] ; H. J. Yang [Corée du Sud]Source :
- Parasitology Research [ 0932-0113 ] ; 2006-12-01.
Abstract
Abstract: Changes of serum cytokines including interferon gamma inducible protein-10 (IP-10) chemokine were analyzed in a total of eight vivax malarial patients before and after chemotherapy by immunostaining for human cytokine antibodies attached to membranes. IP-10 was strongly reactive in the period before chloroquine/primaquine combined chemotherapy and disappeared after chemotherapy in all patients. Therefore, IP-10 chemokine may be of importance in the pathogenesis of vivax malaria and a good marker of a complete cure.
Url:
DOI: 10.1007/s00436-006-0263-3
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: Changes of serum cytokines including interferon gamma inducible protein-10 (IP-10) chemokine were analyzed in a total of eight vivax malarial patients before and after chemotherapy by immunostaining for human cytokine antibodies attached to membranes. IP-10 was strongly reactive in the period before chloroquine/primaquine combined chemotherapy and disappeared after chemotherapy in all patients. Therefore, IP-10 chemokine may be of importance in the pathogenesis of vivax malaria and a good marker of a complete cure.</div>
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